Fremgangsmate for fremstilling av HIV proteaseinhibitorer

Fremgangsmate for fremstilling av HIV proteaseinhibitorer

An improved process for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3 -(4-amino-N-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps form the compound of formula A and a novel intermediate thereto.

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Bibliographische Detailangaben
Hauptverfasser: AL-FARHAN EMILE, RODGERS KEITH, SINGH HARDEV, TUNG ROGER DENNIS, O'CALLAGHAN JOHN MARK, ROUT STEPHEN, DEININGER DAVID D, MCGHIE STEPHEN, ROBERTSON MARK STUART
Format: Patent
Sprache:nor
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:An improved process for the synthesis of (3S)-tetrahydro-3-furyl N-[(1S,2R)-3 -(4-amino-N-isobutylbenzenesulphonamido)-1-benzyl-2-hydroxypropyl]carbamate comprising four steps form the compound of formula A and a novel intermediate thereto.