AnalogifremgangsmÕte for fremstilling av terapeutisk aktive oligonukleotider

Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.

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Bibliographische Detailangaben
Hauptverfasser: RAMALHO-ORTIGAO, JOSE FLAVIO, FRAELICH, ANJA, MONTENARH, MATTHIAS, RAESCH, HANNELORE, SELIGER, HARTMUT
Format: Patent
Sprache:nor
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Zusammenfassung:Therapeutically utilisable oligonucleotides of the formulae I and II are obtained by introducing terminal 3'-3' or 5'-5' linkages. These nuclease-stable compounds suppress the biological function of nucleic acids.