Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on
Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksem...
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| creator | ROESSLER ARMIN VILLANI FRANK J FAESSLER ROGER MEHRMAN STEVEN J HEGYI JEAN FRANCOIS ALEXANDRE LUCAS |
| description | Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksempel depresjon, angst, alkoholmisbruk, osv. Det beskrives videre fremgangsmåter for fremstilling av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fényl])-8-(8-metyl-naftalen-l-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on og dennes tilsvarende salter.
The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts. |
| format | Patent |
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The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts.</description><language>nor</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090821&DB=EPODOC&CC=NO&NR=20092416L$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090821&DB=EPODOC&CC=NO&NR=20092416L$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROESSLER ARMIN</creatorcontrib><creatorcontrib>VILLANI FRANK J</creatorcontrib><creatorcontrib>FAESSLER ROGER</creatorcontrib><creatorcontrib>MEHRMAN STEVEN J</creatorcontrib><creatorcontrib>HEGYI JEAN FRANCOIS ALEXANDRE LUCAS</creatorcontrib><title>Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on</title><description>Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksempel depresjon, angst, alkoholmisbruk, osv. Det beskrives videre fremgangsmåter for fremstilling av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fényl])-8-(8-metyl-naftalen-l-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on og dennes tilsvarende salter.
The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAUQNEuDqL-g24p9EHbVKmzKA5FQd1EyqN9wWKahDQKET_eKn6A04XLGQavI0pHdoqPKQfGAdtGaUiBHUK4-trqW-fBWG28DCEBloGQd20Fqc_IgeXQkvNSoXAoSfXGy-_pecSjHJxt8InQmcbqcxbNLzVVqCADrcbBQKDsaPLrKJht1qfVFsjokjqDFSly5W6fxvEyzZJFUfB_zBvIvULM</recordid><startdate>20090821</startdate><enddate>20090821</enddate><creator>ROESSLER ARMIN</creator><creator>VILLANI FRANK J</creator><creator>FAESSLER ROGER</creator><creator>MEHRMAN STEVEN J</creator><creator>HEGYI JEAN FRANCOIS ALEXANDRE LUCAS</creator><scope>EVB</scope></search><sort><creationdate>20090821</creationdate><title>Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on</title><author>ROESSLER ARMIN ; VILLANI FRANK J ; FAESSLER ROGER ; MEHRMAN STEVEN J ; HEGYI JEAN FRANCOIS ALEXANDRE LUCAS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NO20092416LL3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>nor</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ROESSLER ARMIN</creatorcontrib><creatorcontrib>VILLANI FRANK J</creatorcontrib><creatorcontrib>FAESSLER ROGER</creatorcontrib><creatorcontrib>MEHRMAN STEVEN J</creatorcontrib><creatorcontrib>HEGYI JEAN FRANCOIS ALEXANDRE LUCAS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROESSLER ARMIN</au><au>VILLANI FRANK J</au><au>FAESSLER ROGER</au><au>MEHRMAN STEVEN J</au><au>HEGYI JEAN FRANCOIS ALEXANDRE LUCAS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on</title><date>2009-08-21</date><risdate>2009</risdate><abstract>Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksempel depresjon, angst, alkoholmisbruk, osv. Det beskrives videre fremgangsmåter for fremstilling av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fényl])-8-(8-metyl-naftalen-l-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on og dennes tilsvarende salter.
The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on |
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