Salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluorfenyl)-8-(8-metylnaftalen-1-ylmetyl)-1,3,8-triaza-spiro[4,5]decan-4-on
Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksem...
Gespeichert in:
Hauptverfasser: | , , , , |
---|---|
Format: | Patent |
Sprache: | nor |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Det beskrives salter av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fenyl-8-(8-metyl-naftalen-1-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on. Det beskrives videre farmasøytiske preparater inneholdende disse samt deres anvendelse ved behandling av forstyrrelser og tilstander modulert av NOP, for eksempel depresjon, angst, alkoholmisbruk, osv. Det beskrives videre fremgangsmåter for fremstilling av 3-(3-amino-2-(R)-hydroksy-propyl)-1-(4-fluor-fényl])-8-(8-metyl-naftalen-l-ylmetyl)-1,3,8-triaza-spiro[4.5]dekan-4-on og dennes tilsvarende salter.
The present invention is directed to salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention is further directed to process(es) for the preparation of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl)-1,3,8-triaza-spiro[4.5]decan-4-one and its corresponding salts. |
---|