Quinazoliner for PDK1-inhibering

The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.

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Bibliographische Detailangaben
Hauptverfasser:	Amiri, Payman, Wang, Xiajong M, Dove, Jeffrey, Ng, Simon C, Wagman, Allan S, Subramanian, Sharada, Murray, Jeremy M, Jansen, Johanna M, Basman, Steven E, Jain, Rama, Rico, Alice C, Shu, Wei, Zhou, Yasheen, Wang, Weibo, Aikawa, Mina, Ramurthy, Savithri, Lin, Xiadong, Pfister, Keith B, Warne, Robert L
Format:	Patent
Sprache:	nor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention provides quinazoline compounds that are inhibitors of PDK1. Also provided are pharmaceutical compositions including the compounds, and methods of treating proliferative diseases, such as cancers, with the compounds or compositions.