Osmotisk leveringssystem

An osmotic pharmaceutical tablet is described which comprises a single-layer compressed core surrounded by a water permeable layer having a passageway. The single-layer core contains (i) a non-ripening drug having a solubility per dose less than about 1 mL-1, (ii) about 2.0% to about 20% by weight o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	BILLOTTE ANNE MARTINE, MACDONALD BRUCE, ROY MICHAEL CHRISTOPHER, FERGIONE MICHAEL BRUCE, CARRIER REBECCA LYN, MILLER LEE ANTHONY, SHAMBLIN SHERI LYNN, WATERMAN KENNETH CRAIG, FRIESEN DWAYNE THOMAS
Format:	Patent
Sprache:	nor
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An osmotic pharmaceutical tablet is described which comprises a single-layer compressed core surrounded by a water permeable layer having a passageway. The single-layer core contains (i) a non-ripening drug having a solubility per dose less than about 1 mL-1, (ii) about 2.0% to about 20% by weight of a hydroxyethylcellulose having a weight-average, molecular weight from about 300,000 to about 2,000,000, and (iii) an osmagent.