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The present invention provides compounds having formula (I), wherein R 1 , R 2 , R 3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune an...

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Hauptverfasser: KIKUCHI KOUICHI, DAUN JANE, DAVIS HEATHER A, SOEJIMA MOTOHIRO, JIANG YIMIN, PESANT MARC, LI XIANG-YI, KOBAYSHI SEIICHI, GUSOVSKY FABIAN, KANEKO TOSHIHIKO, SELETSKY BORIS M, MURAMOTO KENZO, OHI NORIHITO, TREMBLEY LYNDA, YOKOHAMA HIROMITSU, ZHENG WANJUN, LESCARBEAU ANDRE, DECOSTA BRUCE F, HISHINUMA IEHARU, YAO YE
Format: Patent
Sprache:nor
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Zusammenfassung:The present invention provides compounds having formula (I), wherein R 1 , R 2 , R 3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.