2-amino-6-(2,4,5 -substituerte-fenyl)-pyridiner for anvendelse som nitrogenoksyd syntase inhibitorer

Det er beskrevet forbindelsene 6-[4-(N-metyl-3azetidinoksy)-5-etyl-2-metoksy-fenyl]-pyridin-2-ylamin, 6- [4-(N,N-dimetyIaniinometyl)-5 -etyl-2-metoksy-fenyl] -pyridin-2-ylamin, 6- [4-(N-metyllaminometyi)-5-ety 1-2-metoksy-fenyl]-pyridin-2-ylamin, 6-[4-(3-azetidinoksy)-5-etyl-2-metoksy-fenyl]-pyridin2-ylamin og 6-[4(2-dimetylamino-etoksy)-5-etyl-2-metoksy-fenyl]-pyridin-2-ylaniin, og farmasøytisk akseptable salter derav, farmasøytiske sammensetninger inneholdende slike forbindelser og anvendelser av slike forbindelser som nitrogenoksidsyntaseinhibitorer ved behandling og forebygging av sentralnervesystemet og andre forstyrrelser. The present invention relates to the compounds 6-[4-(N-methyl-3-azetidinoxy)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, 6-[4-(N, N-dimethylaminomethyl)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, 6-[4-(N-methylaminomethyl)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, 6-[4-(3-azetidinoxy)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine and 6-[4-(2-dimethylamino-ethoxy)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine, and the pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing such compounds and to the use of such compounds as nitric oxide synthase inhibitors in the treatment and prevention of central nervous system and other disorders.