Fremgangsmåte for fremstilling av modifisert Eglin B eller C samt DNA, ekspresjonsvektor og vertsmikroorganisme

Eglin mutants which differ from natural eglins B and C in that one, two or three amino acids in the region of the active centre (amino acids 45 and 46, Leu-Asp) have been replaced by other amino acids are provided. The mutants, which can be prepared by recombinant gene techniques, have valuable phar...

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Bibliographische Detailangaben
Hauptverfasser:	GRUTTER, MARKUS GERHARD, HEINZ, DIRK, LIERSCH, MANFRED
Format:	Patent
Sprache:	nor
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Eglin mutants which differ from natural eglins B and C in that one, two or three amino acids in the region of the active centre (amino acids 45 and 46, Leu-Asp) have been replaced by other amino acids are provided. The mutants, which can be prepared by recombinant gene techniques, have valuable pharmacological properties.