FREMGANGSMAATE VED FREMSTILLING AV HUDERSTATNING

The method for obtaining a skin equivalent (27) involves preparing a dermis equivalent (24) by mixing contractile cells, a nutrient medium and collagen so as to form a gel which contracts; using this dermis equivalent (24) as a substrate for an epidermis equivalent (26) obtained by sowing with the k...

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Bibliographische Detailangaben
Hauptverfasser: LENOIR, MARIE-CECILE, BERNARD, BRUNO, DARMON, YVES-MICHEL, SHROOT, BRAHAM, ASSELINEAU, DANIEL
Format: Patent
Sprache:nor
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Beschreibung
Zusammenfassung:The method for obtaining a skin equivalent (27) involves preparing a dermis equivalent (24) by mixing contractile cells, a nutrient medium and collagen so as to form a gel which contracts; using this dermis equivalent (24) as a substrate for an epidermis equivalent (26) obtained by sowing with the keratinocytes from an animal or human explant. According to the invention, the substrate (24) is sown with at least one section of a hair follicle (22) comprising at least partially its cellular sheath, the said section being implanted substantially perpendicular to the free surface of the substrate.