ANALOGIFREMGANGSMAATE VED FREMSTILLING AV TERAPEUTISK AKTIVE (4A,11B)-3,4,4A,5,6,11B-HEXAHYDRO-2H-(1)-BENZOXEPINO-(5,4-B)-1,4-OXAZINDERIVATER

ANALOGIFREMGANGSMAATE VED FREMSTILLING AV TERAPEUTISK AKTIVE (4A,11B)-3,4,4A,5,6,11B-HEXAHYDRO-2H-(1)-BENZOXEPINO-(5,4-B)-1,4-OXAZINDERIVATER

Derivatives of 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, such as (4a,11b)-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazine, are prepared by acylating a 4-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol, cyclizing the resulting chloroacetamido alcohol, reducing the 1,4-oxazine-3(4H)-one so obtain...

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Bibliographische Detailangaben
1. Verfasser: FREEDMAN, JULES
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Derivatives of 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, such as (4a,11b)-3,4,4a,5,6,11b-hexahydro-2H-[1]benzoxepino[5,4-b]-1,4-oxazine, are prepared by acylating a 4-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ol, cyclizing the resulting chloroacetamido alcohol, reducing the 1,4-oxazine-3(4H)-one so obtained, acylating the resulting 2H-[1]benzoxepino[5,4-b]-1,4-oxazine, and reducing the N-acyl-2H-[1]benzoxepino[5,4-b]-1,4-oxazine so obtained. The novel compounds disclosed herein possess useful muscle relaxant and analgesic properties.