ANALOGIFREMGANGSMAATE TIL FREMSTILLING AV TERAPEUTISK AKTIV 2,6-DIMETYL-4-(2,3-DIKLORFENYL)-1,4-DIHYDROPYRIDIN-3,5-DIKARBOKSYLSYRE-3-METYLESTER-5-ETYLESTER

ANALOGIFREMGANGSMAATE TIL FREMSTILLING AV TERAPEUTISK AKTIV 2,6-DIMETYL-4-(2,3-DIKLORFENYL)-1,4-DIHYDROPYRIDIN-3,5-DIKARBOKSYLSYRE-3-METYLESTER-5-ETYLESTER

The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formulawherein R1 is selected from the group consisting of -CH1, -C2H5, -CH2CH2OCH3, - CH2CH2OC2H5, and (CH2CH2O)2CH3, and R2 is selected from the group consisting of -C2H3, -CH(CH3)2, -C(CH3)3...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LJUNG, BENGT RICHARD, BERNTSSON, PEDER BERNARD, GAARDER, JAN OERNULF, CARLSSON, STIG AAKE INGEMAR
Format: Patent
Sprache:nor
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to new compounds having anti-hypertensive effect, which compounds are of the formulawherein R1 is selected from the group consisting of -CH1, -C2H5, -CH2CH2OCH3, - CH2CH2OC2H5, and (CH2CH2O)2CH3, and R2 is selected from the group consisting of -C2H3, -CH(CH3)2, -C(CH3)3, -CH(CH1)C2H3, -CH2CH2OCH(CH3)2, -CH(CH3)CH2OCH3, C(CH3)2CH2OCH3, -CH2C=CH, and -CH2C(CH3)=CH2, whereby R' and R are not the same, R' is selected from the group consisting of chloro and methoxy, and R' is selected from the group consisting of chloro, methyl, and methoxy, process for the preparation of said compounds, and pharmaceutical preparations containing said compounds.