ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV TERAPEUTISK AKTIVE LACTAM-N-EDDIKSYRER OG DERES AMIDER

New lactam-N-acetic acids and amides thereof having the formula wherein R1 and R2=H, C1-C4-alkyl, aryl or halogen-substituted aryl, R3=OH or -NR4R5, R4 and R5=H, C1-C4-alkyl, cycloalkyl, aralkyl or, taken together with the N atom form alkyleneimino, oxa-alkyleneimino, aza-alkyleneimino or N-benzyl-a...

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Hauptverfasser: MARCHAL, LUCIEN, RODRIGUEZ, LUDOVIC
Format: Patent
Sprache:nor
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Zusammenfassung:New lactam-N-acetic acids and amides thereof having the formula wherein R1 and R2=H, C1-C4-alkyl, aryl or halogen-substituted aryl, R3=OH or -NR4R5, R4 and R5=H, C1-C4-alkyl, cycloalkyl, aralkyl or, taken together with the N atom form alkyleneimino, oxa-alkyleneimino, aza-alkyleneimino or N-benzyl-aza-alkyleneimino, m is 3, 4 or 5, preferably 3, n is 0, 1 or 2, preferably 2; and the pharmaceutically acceptable salts of said acids. Processes for producing these compounds and pharmaceutical compositions containing the same are also given. These compounds show amongst others beneficial activity on the mnemic processes and cardiac activity.