ANALOGIFREMGANGSM}TE TIL FREMSTILLING AV EN TERAPEUTISK VIRKSOM IMIDAZOLIDINON-FORBINDELSE

1383619 1-Azetindinyl-3-phenyl-2-imidazolidinones GRUPPO LEPETIT SpA 13 June 1973 [26 July 1972] 28197/73 Heading C2C Novel compounds I and their acid addition salts in which R, R 1 , R 2 and R 3 are hydrogen or C 1-4 alkyl and X is one or more substituents selected from halogen, C 1-4 alkyl, C 1-4...

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Bibliographische Detailangaben
Hauptverfasser:	FONTANELLA, LUIGI, MAFFII, GIULIO
Format:	Patent
Sprache:	nor
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:	1383619 1-Azetindinyl-3-phenyl-2-imidazolidinones GRUPPO LEPETIT SpA 13 June 1973 [26 July 1972] 28197/73 Heading C2C Novel compounds I and their acid addition salts in which R, R 1 , R 2 and R 3 are hydrogen or C 1-4 alkyl and X is one or more substituents selected from halogen, C 1-4 alkyl, C 1-4 alkoxy or trifluoromethyl are prepared by reacting (1) a compound II or its acetate derivative (prepared by acylation of alkanol), with phosgene and potassium hydroxide and substitition of the hydroxy group by halogen using a thionyl halide. Compounds V are prepared by reduction of the corresponding 2 - [1 - (phenylcarbamyl)alkylamino] - alkanoic