System for generating microvesicles having a predefined size and/or size distribution

System for generating microvesicles having a predefined size and/or size distribution, the system comprising: - a microvesicle generating unit for generating microbubbles having a predefined size and/or size 5 distribution, wherein said microvesicle generating unit comprises an inlet side that is ar...

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Hauptverfasser: PETER JOHAN ANTON FRINKING, GERRITDINA MARIEKE OLSMAN, EWOUT RIK JONKER, JEROEN GERARD RUITER, MARTIJN PETER TIBBE, WOUTER KLEIN HESSELINK
Format: Patent
Sprache:eng
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Zusammenfassung:System for generating microvesicles having a predefined size and/or size distribution, the system comprising: - a microvesicle generating unit for generating microbubbles having a predefined size and/or size 5 distribution, wherein said microvesicle generating unit comprises an inlet side that is arranged for receiving, through a first inlet, a first and, through a second inlet, a second fluid that are to be mixed by the microvesicle generating unit for generating the microvesicles and an outlet side that is arranged downstream and is arranged for expelling generated microvesicles; - means for receiving said generated microvesicles in a microvesicle carrier liquid for obtaining a 10 microvesicle containing heterogeneous mixture; - a holding unit for holding the microvesicle containing heterogeneous mixture comprising the generated microvesicles and the microvesicle carrier liquid, in particular a saline solution; - a uniformization mechanism that is arranged for continuously uniformizing of the microvesicle containing heterogeneous mixture held in the holding unit.