PREPARATION AND ANTI-TUMOR APPLICATION OF BIOTIN TARAXASTEROL DERIVATIVES

The present invention relates to the technical field of medicine, in particular to an application. of biotin-binding taraxasterol derivatives (Bio-TS) in preparing anti-tumor drugs. Biotin-binding taraxasterol (Bio-TS) is an original invention of our laboratory 5 and a substance independently synthe...

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Bibliographische Detailangaben
Hauptverfasser: PINGXIN ZHOU, JINGLI SHANG, TIESUO ZHAO, YUANHUA QIN, YU ZHANG, JIAN LI, CHUNPO GE, FENG REN
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to the technical field of medicine, in particular to an application. of biotin-binding taraxasterol derivatives (Bio-TS) in preparing anti-tumor drugs. Biotin-binding taraxasterol (Bio-TS) is an original invention of our laboratory 5 and a substance independently synthesized by the laboratory. The in vivo and in vitro experiments in the present invention verify the safety of Bio-TS in cells and mice, and verify that Bio-TS can significantly inhibit the proliferation of tumor cells and promote the apoptosis; Bio-TS drugs can inhibit the proliferation of tumor 10 cells.