COMPOUNDS FOR TREATMENT OF HEART FAILURE

The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of heart failure with reduced ejection fraction (HFrEF). Specifically, the present invention relates to chromanol compounds chosen from S-(6- hydroxy-2,5,7,8-tetramethylchroman-2yl)(pi...

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Bibliographische Detailangaben
Hauptverfasser:	LUCAS MORITZ WIGGENHAUSER, GUIDO KRENNING, ROBERT HENK HENNING, ADRIANUS CORNELIS VAN DER GRAAF
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to certain chromanol, quinone or hydroquinone compounds and derivatives thereof for treatment of heart failure with reduced ejection fraction (HFrEF). Specifically, the present invention relates to chromanol compounds chosen from S-(6- hydroxy-2,5,7,8-tetramethylchroman-2yl)(piperazin-l-yl)methanone and S-(6-hydroxy- 2, 5,7, 8-tetramethylchroman-2-yl)(4-(2-hydroxyethyl)piperazin- l -yl)methanone, and pharmaceutically acceptable salts thereof.