Conjugaten van glycerol-vertakt polyethyleenglycol en menselijk groeihormoon, werkwijzen voor de bereiding daarvan en werkwijzen voor gebruik daarvan

The present invention relates to PEGylation of human Growth Hormone (hGH) using a glycerol branched PEG. The present invention also relates to processes for the PEGylation of hGH. In addition, the present invention relates to pharmaceutical compositions comprising the PEGylated hGH. A further embodi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	RORY FRANCIS FINN, NED ROGER SIEGEL
Format:	Patent
Sprache:	dut
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to PEGylation of human Growth Hormone (hGH) using a glycerol branched PEG. The present invention also relates to processes for the PEGylation of hGH. In addition, the present invention relates to pharmaceutical compositions comprising the PEGylated hGH. A further embodiment is the use of the PEGylated hGH for the treatment of growth and development disorders.