Benzopyranverbindingen toepasbaar voor het behandelen van ontstekingsaandoeningen

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the...

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Hauptverfasser: ANGELA M. DEPROW, DAVID LOUIS BROWN, YI YU, JEFFERY STEVEN CARTER, RENEE M. HUFF, JAMES RICHARD KIEFER, JR, SUBO LIAO, BRUCE CAMERON HAMPER, JOHN ROBERT SPRINGER, KARL WILLIAM ASTON, E. ANN HALLINAN, LIJUAN JANE WANG, LI XING, DAVID CHRISTOPHER LIMBURG, THERESA R. FLETCHER, STEVEN W. KRAMER, JOHN T. TALLEY, JOHN MICHAEL MCCALL, FRANCIS KOSZYK, CINDY LUDWIG
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creator ANGELA M. DEPROW
DAVID LOUIS BROWN
YI YU
JEFFERY STEVEN CARTER
RENEE M. HUFF
JAMES RICHARD KIEFER, JR
SUBO LIAO
BRUCE CAMERON HAMPER
JOHN ROBERT SPRINGER
KARL WILLIAM ASTON
E. ANN HALLINAN
LIJUAN JANE WANG
LI XING
DAVID CHRISTOPHER LIMBURG
THERESA R. FLETCHER
STEVEN W. KRAMER
JOHN T. TALLEY
JOHN MICHAEL MCCALL
FRANCIS KOSZYK
CINDY LUDWIG
description The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Benzopyranverbindingen toepasbaar voor het behandelen van ontstekingsaandoeningen
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