Benzopyranverbindingen toepasbaar voor het behandelen van ontstekingsaandoeningen

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the...

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Hauptverfasser: ANGELA M. DEPROW, DAVID LOUIS BROWN, YI YU, JEFFERY STEVEN CARTER, RENEE M. HUFF, JAMES RICHARD KIEFER, JR, SUBO LIAO, BRUCE CAMERON HAMPER, JOHN ROBERT SPRINGER, KARL WILLIAM ASTON, E. ANN HALLINAN, LIJUAN JANE WANG, LI XING, DAVID CHRISTOPHER LIMBURG, THERESA R. FLETCHER, STEVEN W. KRAMER, JOHN T. TALLEY, JOHN MICHAEL MCCALL, FRANCIS KOSZYK, CINDY LUDWIG
Format: Patent
Sprache:dut
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Zusammenfassung:The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.