Chinoline- en chinoxalineverbindingen

Chinoline- en chinoxalineverbindingen

Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower c...

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Bibliographische Detailangaben
Hauptverfasser: DAVID AUSTEN PERRY, RYAN MICHAEL KELLEY, MARY THERESA DIDIUK, JARI IIMARI FINNEMAN, GEORGE CHANG, RAVI SHANKER GARIGIPATI, BRUCE MICHAEL BECHLE, ROGER BENJAMIN RUGGERI
Format: Patent
Sprache:dut
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.