SALTS OF PENICILLANIC ACID 1, 1-DIOXIDE

SALTS OF PENICILLANIC ACID 1, 1-DIOXIDE

Novel 1:2 N,N min -dibenzylethylenediamine, N-benzyl-2-phenylethylamine and dibenzylamine salts of penicillanic acid 1,1-dioxide are prepared which are sparingly soluble in water and therefore valuable as slow release (depot) forms of penicillanic acid 1,1-dioxide, particularly for use in conjunctio...

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Bibliographische Detailangaben
Hauptverfasser: MOPPETT, CHARLES EDWARD, WINDISCH, WENDELL WILLIAM, ARMSTRONG, WILLIAM WELLESLEY
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Novel 1:2 N,N min -dibenzylethylenediamine, N-benzyl-2-phenylethylamine and dibenzylamine salts of penicillanic acid 1,1-dioxide are prepared which are sparingly soluble in water and therefore valuable as slow release (depot) forms of penicillanic acid 1,1-dioxide, particularly for use in conjunction with slow release (depot) forms of penicillin and cephalosporin antibiotics, in the chemotherapy of bacterial infections in mammals.