TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described...
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creator | KWONG WAH LAI XIAOJING WANG Zhiguo Liu SIMON CHARLES GOODACRE Jiangpeng Liao John Sui-Man Wai Tao Wang DANIEL FRED ORTWINE JUN LIANG NICHOLAS CHARLES RAY SHARADA LABADIE JASON ZBIEG BIRONG ZHANG Jun Li |
description | Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors. |
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Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230828&DB=EPODOC&CC=MY&NR=198354A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230828&DB=EPODOC&CC=MY&NR=198354A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KWONG WAH LAI</creatorcontrib><creatorcontrib>XIAOJING WANG</creatorcontrib><creatorcontrib>Zhiguo Liu</creatorcontrib><creatorcontrib>SIMON CHARLES GOODACRE</creatorcontrib><creatorcontrib>Jiangpeng Liao</creatorcontrib><creatorcontrib>John Sui-Man Wai</creatorcontrib><creatorcontrib>Tao Wang</creatorcontrib><creatorcontrib>DANIEL FRED ORTWINE</creatorcontrib><creatorcontrib>JUN LIANG</creatorcontrib><creatorcontrib>NICHOLAS CHARLES RAY</creatorcontrib><creatorcontrib>SHARADA LABADIE</creatorcontrib><creatorcontrib>JASON ZBIEG</creatorcontrib><creatorcontrib>BIRONG ZHANG</creatorcontrib><creatorcontrib>Jun Li</creatorcontrib><title>TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF</title><description>Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAJcQ0JcvSIdAny1w2IDPJ08Y821jHRdYr19HPx93FVcA0OCfJ3d_VTCHJ1dg0I8Q9S8PV3CfVxBLKCFRz9XBRCg12DFUI8XINc_d14GFjTEnOKU3mhNDeDnJtriLOHbmpBfnxqcUFicmpeakm8b6ShpYWxqYmjMUEFAPboLWc</recordid><startdate>20230828</startdate><enddate>20230828</enddate><creator>KWONG WAH LAI</creator><creator>XIAOJING WANG</creator><creator>Zhiguo Liu</creator><creator>SIMON CHARLES GOODACRE</creator><creator>Jiangpeng Liao</creator><creator>John Sui-Man Wai</creator><creator>Tao Wang</creator><creator>DANIEL FRED ORTWINE</creator><creator>JUN LIANG</creator><creator>NICHOLAS CHARLES RAY</creator><creator>SHARADA LABADIE</creator><creator>JASON ZBIEG</creator><creator>BIRONG ZHANG</creator><creator>Jun Li</creator><scope>EVB</scope></search><sort><creationdate>20230828</creationdate><title>TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF</title><author>KWONG WAH LAI ; XIAOJING WANG ; Zhiguo Liu ; SIMON CHARLES GOODACRE ; Jiangpeng Liao ; John Sui-Man Wai ; Tao Wang ; DANIEL FRED ORTWINE ; JUN LIANG ; NICHOLAS CHARLES RAY ; SHARADA LABADIE ; JASON ZBIEG ; BIRONG ZHANG ; Jun Li</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_MY198354A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KWONG WAH LAI</creatorcontrib><creatorcontrib>XIAOJING WANG</creatorcontrib><creatorcontrib>Zhiguo Liu</creatorcontrib><creatorcontrib>SIMON CHARLES GOODACRE</creatorcontrib><creatorcontrib>Jiangpeng Liao</creatorcontrib><creatorcontrib>John Sui-Man Wai</creatorcontrib><creatorcontrib>Tao Wang</creatorcontrib><creatorcontrib>DANIEL FRED ORTWINE</creatorcontrib><creatorcontrib>JUN LIANG</creatorcontrib><creatorcontrib>NICHOLAS CHARLES RAY</creatorcontrib><creatorcontrib>SHARADA LABADIE</creatorcontrib><creatorcontrib>JASON ZBIEG</creatorcontrib><creatorcontrib>BIRONG ZHANG</creatorcontrib><creatorcontrib>Jun Li</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KWONG WAH LAI</au><au>XIAOJING WANG</au><au>Zhiguo Liu</au><au>SIMON CHARLES GOODACRE</au><au>Jiangpeng Liao</au><au>John Sui-Man Wai</au><au>Tao Wang</au><au>DANIEL FRED ORTWINE</au><au>JUN LIANG</au><au>NICHOLAS CHARLES RAY</au><au>SHARADA LABADIE</au><au>JASON ZBIEG</au><au>BIRONG ZHANG</au><au>Jun Li</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF</title><date>2023-08-28</date><risdate>2023</risdate><abstract>Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF |
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