TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

TETRAHYDRO-PYRIDO[3,4-B]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described...

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Bibliographische Detailangaben
Hauptverfasser: KWONG WAH LAI, XIAOJING WANG, Zhiguo Liu, SIMON CHARLES GOODACRE, Jiangpeng Liao, John Sui-Man Wai, Tao Wang, DANIEL FRED ORTWINE, JUN LIANG, NICHOLAS CHARLES RAY, SHARADA LABADIE, JASON ZBIEG, BIRONG ZHANG, Jun Li
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: [Formula I] and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.