COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND A METHOD FOR THE PROPHYLAXIS AND TREATMENT OF THE ADHESION PROCESS

The invention relates to the field of pharmacy, clinical and experimental medicine and veterinary medicine, and in particular to novel inhibitory compounds of a p38 MAP kinase having a structure of type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. The invention discloses...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHURYGINA, IRINA ALEKSANDROVNA, SHURYGIN, MIKHAIL GENNADIEVICH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to the field of pharmacy, clinical and experimental medicine and veterinary medicine, and in particular to novel inhibitory compounds of a p38 MAP kinase having a structure of type (I)-(VII) which can be used for the treatment or prophylaxis of adhesion. The invention discloses pharmaceutical compositions containing an effective amount of the substance SB203580 or one or more of the conjugated compounds of type (I)-(VII) or a combination thereof, and a pharmaceutically acceptable carrier, a diluent or an excipient. Also disclosed is the use of the substance SB203580 as an agent having anti- adhesion activity. Also disclosed is a method for the prophylaxis and/or treatment of a disease or a condition in which there is a possibility of the formation and/or growth of adhesions, which makes it possible to dispense with the additional administration of a preparation in the post-operative period.