SUSPENSION COMPOSITIONS OF CYCLOSPORIN A FOR SUBCONJUNCTIVAL AND PERIOCULAR INJECTION

SUSPENSION COMPOSITIONS OF CYCLOSPORIN A FOR SUBCONJUNCTIVAL AND PERIOCULAR INJECTION

The present disclosure relates to suspension formulations and systems for the treatment of ocular conditions. The suspension formulations can include cyclosporin A and in some embodiments, Form 1 or Form 2 cyclosporin A. A delivery system can be provided that includes two parts, a first part contain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: NEERVANNAN, SESHA, WU, KE, PUJARA, CHETAN P, GORE, ANURADHA V, HOU, HAO
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure relates to suspension formulations and systems for the treatment of ocular conditions. The suspension formulations can include cyclosporin A and in some embodiments, Form 1 or Form 2 cyclosporin A. A delivery system can be provided that includes two parts, a first part containing particles of cyclosporin and a second part containing other components that can be combined with the first part to make a suspension formulation. The suspension can be injected into the subconjunctival or other periocular space to treat ocular conditions, such as dry eye disease.