BIOSYNTHETIC HEPARIN

BIOSYNTHETIC HEPARIN

The present disclosure relates to synthesis of heparin, which may be bioequivalent to porcine USP Heparin Sodium. The synthesis may involve three intermediates starting from heparosan. Figure 1

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Bibliographische Detailangaben
Hauptverfasser: DORDICK, Jonathan, BRODFUEHRER, Paul, MORI, Daisuke, FU, Li, DATTA, Payel, LIN, Lei, GROVER, Navdeep, PASKALEVA, Elena, DOUAISI, Marc, LI, Kevin, HIRAKANE, Makoto, ONISHI, Akihiro, SIMMONS, Trevor J, LINHARDT, Robert J
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The present disclosure relates to synthesis of heparin, which may be bioequivalent to porcine USP Heparin Sodium. The synthesis may involve three intermediates starting from heparosan. Figure 1