4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AND 4-IMIDAZOTRIAZIN-1-YL-BENZAMIDES AS BTK-INHIBITORS

4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AND 4-IMIDAZOTRIAZIN-1-YL-BENZAMIDES AS BTK-INHIBITORS

The present invention relates to 6-5 membered fused pyridine ring compounds according to formula I FORMULA I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use...

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Bibliographische Detailangaben
Hauptverfasser: STERRENBURG, JAN-GERARD, JANS, CHRISTIAAN, GERARDUS, JOHANNES, MARIA, BARF, TJEERD A, MAN, DE ADRIANUS, PETRUS, ANTONIUS, REWINKEL, JOHANNES, BERNARDUS, MARIA, OUBRIE, ARTHUR A, RAAIJMAKERS HANS C.A
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to 6-5 membered fused pyridine ring compounds according to formula I FORMULA I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of 6- 5 membered fused pyridine ring compounds according to formula I in the treatment of Bruton's Tyrosine Kinase (Btk) mediated disorders.