COMBINATION FORMULATION CONTAINING SUSTAINED RELEASE METFORMIN AND IMMEDIATE RELEASE HMG-COA REDUCTASE INHIBITOR

ABSTRACT THE PRESENT INVENTION RELATES TO A COMBINATION FORMULATION CONTAINING METFORMIN FOR TREATING NON-INSULIN-DEPENDENT DIABETES AND AN HMG-COA REDUCTASE INHIBITOR FOR TREATING DYSLIPIDEMIA. THE PRESENT INVENTION PROVIDES A COMBINATION FORMULATION AND A METHOD FOR PREPARING THE COMBINATION FORMU...

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Hauptverfasser: KIM, YU JEONG, OH, TACK OON, LEE, JI EUN, PARK, YOUNG JOON, YOON, SEOK KEE, PARK, JUN HONG, CHO, TAE KEUN, KANG, KWI MAN
Format: Patent
Sprache:eng
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Zusammenfassung:ABSTRACT THE PRESENT INVENTION RELATES TO A COMBINATION FORMULATION CONTAINING METFORMIN FOR TREATING NON-INSULIN-DEPENDENT DIABETES AND AN HMG-COA REDUCTASE INHIBITOR FOR TREATING DYSLIPIDEMIA. THE PRESENT INVENTION PROVIDES A COMBINATION FORMULATION AND A METHOD FOR PREPARING THE COMBINATION FORMULATION, WHEREIN THE COMBINATION FORMULATION CONTAINS METFORMIN AND AN HMG-COA REDUCTASE INHIBITOR, AND HAS EFFECTIVELY IMPROVED STABILITY BY BLOCKING PHYSICAL AND CHEMICAL REACTIONS BETWEEN THE ACTIVE INGREDIENTS WHILE SECURING THE STABLE RELEASE OF RESPECTIVE ACTIVE INGREDIENTS. (FIG. 1)