A MICRONEEDLE PATCH FORMULATION FOR DELIVERING AN ACTIVE INGREDIENT TO SKIN

A MICRONEEDLE PATCH FORMULATION FOR DELIVERING AN ACTIVE INGREDIENT TO SKIN

The present invention relates to a microneedle patch composition comprising one or more microneedles each comprising (a) a tapered tip portion containing a therapeutically active ingredient dispersed in a matrix of a biodegradable polymer capable of providing sustained release of the therapeutically...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CREAN, ABINA, PETERSSON, KARSTEN, MOORE, ANNE, O'SULLIVAN, CAROLINE, ENGELL, KAREN MARGRETHE, NIELSEN, KIM TROENSEGAARD, JANSSON, JORGEN, ERIKSSON, ANDRE HUSS, VUCEN, SONJA
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to a microneedle patch composition comprising one or more microneedles each comprising (a) a tapered tip portion containing a therapeutically active ingredient dispersed in a matrix of a biodegradable polymer capable of providing sustained release of the therapeutically active ingredient over a period of at least two days after insertion of the microneedle or microneedles into the skin, and (b) a fast dissolving microneedle backing layer portion containing a water-soluble polymer overlayering the tip portion, said microneedle or microneedles being attached to and extending from an adhesive surface of a removable substrate. Fig. 1a