TARGETED/IMMUNOMODULATORY FUSION PROTEINS AND METHODS FOR MAKING SAME

The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory...

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Bibliographische Detailangaben
Hauptverfasser: SASTRY, Kedarnath, GOVINDAPPA, Nagaraj, SOARES, Maria, Melina
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates generally to the field of generating fusion proteins to be used in cancer therapy, and more specifically, to nucleotide sequences encoding the fusion proteins, wherein the chimeric fusion proteins comprises at least one targeting moiety and at least one immunomodulatory moiety that counteracts the immune tolerance of cancer cells.