PHARMACEUTICAL COMPOSITIONS COMPRISING AN INTEGRIN ALPHA4 ANTAGONIST FOR USE IN TREATING OCULAR INFLAMMATORY CONDITIONS
The invention relates to antagonists of integrin ?4 and their use in pharmaceutical compositions, primarily topically administered ophthalmic compositions. The pharmaceutical compositions are useful for treating ocular inflammatory conditions, such as dry eye disease, non-infectious uveitis (e.g., a...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The invention relates to antagonists of integrin ?4 and their use in pharmaceutical compositions, primarily topically administered ophthalmic compositions. The pharmaceutical compositions are useful for treating ocular inflammatory conditions, such as dry eye disease, non-infectious uveitis (e.g., anterior, intermediate, posterior, pan-uveitis), non-infectious conjunctivitis, iritis, or scleritis in animals, and particularly mammals, including humans. |
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