3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO[4,5-D] PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF

3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO[4,5-D] PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF

The invention is dired to a 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs tha thave immunomodulatory activity. The invention is also directed to the therapeutic or prophylatic use of such compounds and pharmaceutical compositions c...

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Bibliographische Detailangaben
Hauptverfasser: STEPHEN E. WEBBER, ERIK J. RUEDEN, JOSEPH R. LENNOX, ALAN X. XIANG, GREGORY J. HALEY
Format: Patent
Sprache:eng
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Zusammenfassung:The invention is dired to a 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs tha thave immunomodulatory activity. The invention is also directed to the therapeutic or prophylatic use of such compounds and pharmaceutical compositions containing them, and to methos of treating diseases and disorders described herein, by administering effective amoungs of such compounds and prodrugs.