CLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

CLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

COMPOUNDS OF FORMULA (IA) AND FORMULA (IB) WHEREIN R1,R2,R3,R4,R5, AND R6 ARE AS DEFINED HEREIN FOR FORMULA (IA) OR FORMULA (IB), OR A TAUTOMER, PRODRUG, SOLVATE, OR SALT THEREOF; PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF MODULATING THE GLOCOCORTICOID RECEPTOR FUNCTION AN...

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Hauptverfasser: HOSSEIN RAZAVI, THOMAS A. GILMORE, THOMAS M. KIRRANE, DAVID S. THOMSON, RAJASHEKHAR BETAGERI, HIDENORI TAKAHASHI, MARIO G. CARDOZO, YOUNES BEKKALI, CHRISTIAN HANKE JUSTUS JOACHIM HARCKEN, DORIS RIETHER, JI WANG, JOHN R. PROUDFOOT, DANIEL KUZMICH, RENEE ZINDELL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:COMPOUNDS OF FORMULA (IA) AND FORMULA (IB) WHEREIN R1,R2,R3,R4,R5, AND R6 ARE AS DEFINED HEREIN FOR FORMULA (IA) OR FORMULA (IB), OR A TAUTOMER, PRODRUG, SOLVATE, OR SALT THEREOF; PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF MODULATING THE GLOCOCORTICOID RECEPTOR FUNCTION AND METHODS OF TREATING DISEASE-STATES OR CONDITIONS MEDIATED BY THE GLUCOCORTICOID RECEPTOR FUNCTION OR CHARACTERIZED BY INFLAMMATORY, ALLERGIC, OR PROLIFERATIVE PROCESSES IN A PATIENT USING THESE COMPOUNDS.