NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO[1,2-a][1,4]-BENZODIAZEPINES AND 6H-PYRROLO[1,2-a][1,4]BENZODIAZEPINES SUBSTITUTED WITH BICYCLIC BENZENE DERIVATIVES

THE PRESENT INVENTION IS CONCERNED WITH NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO-[1 ,2-A][1,4]BENZODIAZEPINES AND 6H-PYRROLO[1 ,2-A](1,4)BENZODIAZEPINES SUBSTITUTED WITH BICYCLIC BENZENE DERIVATIVES OF FORMULA (I) WHEREIN R1, R2, R3, R4, R5. R6 AND R7 HAVE THE MEANING DEFINED IN THE CLAIMS. THE COMPO...

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Hauptverfasser: DE WIT, KELLY, MAES, LOUIS, JULES, ROGER, MARIE, MEERPOEL, LIEVEN
Format: Patent
Sprache:eng
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Zusammenfassung:THE PRESENT INVENTION IS CONCERNED WITH NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO-[1 ,2-A][1,4]BENZODIAZEPINES AND 6H-PYRROLO[1 ,2-A](1,4)BENZODIAZEPINES SUBSTITUTED WITH BICYCLIC BENZENE DERIVATIVES OF FORMULA (I) WHEREIN R1, R2, R3, R4, R5. R6 AND R7 HAVE THE MEANING DEFINED IN THE CLAIMS. THE COMPOUNDS ACCORDING TO THE PRESENT INVENTION ARE ACTIVE MAINLY AGAINST DERMATOPHYTES AND SYSTEMIC FUNGAL INFECTIONS. THE INVENTION FURTHER RELATES TO PROCESSES FOR PREPARING SUCH NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAID COMPOUNDS AS AN ACTIVE INGREDIENT AS WELL AS THE USE OF SAID COMPOUNDS AS A MEDICAMENT. (NO SUITABLE