NEW VACCINE FORMULATIONS COMPRISING SAPONIN-CONTAINING ADJUVANTS

THE PRESENT INVENTION PROVIDES FOR A NOVEL OIL-IN-WATER (01W) EMULSION, WITH INCREASED STABILITY IN THE PRESENCE OF BACTERIAL OR VIRAL SUSPENSIONS, ESPECIALLY THOSE CONCENTRATED AND NON-PURIFIED (CRUDE EXTRACTS) OR MINIMALLY PURIFIED. THE EMULSION OF THE PRESENT INVENTION CAN ACT AS VEHICLE FOR THE DELIVERY OF A PHARMACEUTICAL COMPOSITION COMPRISING AT LEAST ONE IMMUNOGEN AND, IN PARTICULAR, AN IMMUNOGEN SELECTED FROM THE GROUP CONSISTING OF AN INACTIVATED PATHOGEN, AN ATTENUATED PATHOGEN, A SUBUNIT, A RECOMBINANT EXPRESSION VECTOR, AND A PLASMID OR COMBINATIONS THEREOF.