DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-1H-INDOL-3-YL]-METHANONES

DISUBSTITUTED [4-(5-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL]-1H-INDOL-3-YL]-METHANONES

THE PRESENT INVENTION EXTENDS TO THE COMPOUND OF FORMULA I: OR A PRODRUG, PHARMACEUTICALLY ACCEPTABLE SALT, OR SOLVATE OF SAID COMPOUND. FURTHERMORE, THE PRESENT INVENTION IS DIRECTED TO A PHARMACEUTICAL COMPOSITION COMPRISING A PHARMACEUTICALLY EFFECTIVE AMOUNT OF THE COMPOUND OF FORMULA I, AND A P...

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Bibliographische Detailangaben
Hauptverfasser: LIANG, GUYAN, STOKLOSA, GREGORY, T, GARDNER, CHARLES, J, POLI, GREGORY, B, ZHAO, ZHICHENG, CHOI-SLEDESKI, YONG-MI, SHUM, PATRICK, WAI-KWOK
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:THE PRESENT INVENTION EXTENDS TO THE COMPOUND OF FORMULA I: OR A PRODRUG, PHARMACEUTICALLY ACCEPTABLE SALT, OR SOLVATE OF SAID COMPOUND. FURTHERMORE, THE PRESENT INVENTION IS DIRECTED TO A PHARMACEUTICAL COMPOSITION COMPRISING A PHARMACEUTICALLY EFFECTIVE AMOUNT OF THE COMPOUND OF FORMULA I, AND A PHARMACEUTICALLY ACCEPTABLE CARRIER. FURTHERMORE, THE PRESENT INVENTION IS DIRECTED TO THE USE OF A COMPOUND OF FORMULA I AS AN INHIBITOR OF TRYPTASE, COMPRISING INTRODUCING THE COMPOUND INTO A COMPOSITION COMPRISING TRYPTASE. IN ADDITION, THE PRESENT INVENTION IS DIRECTED TO THE USE OF A COMPOUND OF FORMULA I FOR TREATING A PATIENT SUFFERING FROM, OR SUBJECT TO, A PHYSIOLOGICAL CONDITION IN NEED OF AMELIORATION OF AN INHIBITOR OF TRYPTASE COMPRISING ADMINISTERING TO THE PATIENT A THERAPEUTICALLY EFFECTIVE AMOUNT OF THE COMPOUND OF CLAIM 1. THE PRESENT INVENTION IS DIRECTED ALSO TO THE PREPARATION OF A COMPOUND OF FORMULA I.