HYDROXY TETRAHYDRO-NAPHTHALENYLUREA DERIVATIVES

THE TETRAHYDRO-NAPHTHALENE DERIVATIVES OF THE PRESENT INVENTION HAVE AN EXCELLENT ACTIVITY AS VR1 ANTAGONIST AND USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISEASES ASSOCIATED WITH VR1 ACTIVITY, IN PARTICULAR FOR THE TREATMENT OF URGE URINARY INCONTINENCE, OVERACTIVE BLADDER, CHRONIC PAIN, NEUROPAT...

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Hauptverfasser:	YASUHIRO TSUKIMI, MASAHIRO SHIROO, TOSHIYA MORIWAKI, KLAUS URBAHNS, TSUTOMU MASUDA, NORIYUKI YAMAMOTO, TOSHIO KOKUBO, HIROSHI FUJISHIMA, NAGAHIRO YOSHIDA, MUNETO MOGI, TAKESHI YURA, MASAOMI TJIMI
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	THE TETRAHYDRO-NAPHTHALENE DERIVATIVES OF THE PRESENT INVENTION HAVE AN EXCELLENT ACTIVITY AS VR1 ANTAGONIST AND USEFUL FOR THE PROPHYLAXIS AND TREATMENT OF DISEASES ASSOCIATED WITH VR1 ACTIVITY, IN PARTICULAR FOR THE TREATMENT OF URGE URINARY INCONTINENCE, OVERACTIVE BLADDER, CHRONIC PAIN, NEUROPATHIC PAIN, POSTOPERATIVE PAIN, RHEUMATOID ARTHRITIC PAIN, NEURALGIA, NEUROPATHIES, ALGESIA, NERVE INJURY, ISCHAEMIA, NEURODEGENERATION, STROKE, INCONTINENCE, INFLAMMATORY DISORDERS SUCH AS ASTHMA AND COPD.