PHARMACEUTICAL COMPOSITIONS WITH CAPACITY TO INDUCE ADOPTOSIS IN TUMOR CELLS FOR THE DIAGNOSIS AND TREATMENT OF THE B-CELL CHRONICLYMPHOCYTIC LEUKEMIA

THE PRESENT INVENTION IS RELATED TO THE BRANCH OF IMMUNOLOGY AND PARTICULARLY WITH THE GENERATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING A HUMANIZED MONOCLONAL ANTIBODY RECOGNIZING THE LEUKOCYTE DIFFERENTIATION ANTIGEN CD6. ACCORDINGLY WITH THAT STATEMENT, THE PURPOSE OF THIS INVENTION IS TO PROV...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	PÉREZ RODRIGUEZ, ROLANDO, MONTERO CASIMIRO, JOSE ENRIQUE, ALONSO RAMÍREZ, RUBY
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	THE PRESENT INVENTION IS RELATED TO THE BRANCH OF IMMUNOLOGY AND PARTICULARLY WITH THE GENERATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING A HUMANIZED MONOCLONAL ANTIBODY RECOGNIZING THE LEUKOCYTE DIFFERENTIATION ANTIGEN CD6. ACCORDINGLY WITH THAT STATEMENT, THE PURPOSE OF THIS INVENTION IS TO PROVIDE PHARMACEUTICAL COMPOSITIONS COMPRISING A HUMANIZED ANTI-CD6 MONOCLONAL ANTIBODY FOR THE DIAGNOSIS AND TREATMENT OF LYMPHOPROLIFERATIVE SYNDROMES AND PARTICULARLY THE B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA. THE ESSENCE OF THE INVENTION CONSIST IN THE APPLICATION OF A HUMANIZED MONOCLONAL ANTIBODY THAT RECOGNIZES THE CD6 ANTIGEN, THE GENERATION OF PHARMACEUTICAL COMPOSITIONS COMPRISING THAT ANTIBODY BEING ABLE TO INDUCE APOPTOSIS OF MALIGNANT CELLS FROM B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS, REACHING A CLINICAL AND A HISTOLOGICAL ANTITUMOR EFFICACY. THE FIELD OF APPLICATION OF THE PRESENT INVENTION EXTENDS TO THE ONCOLOGY.