ORAL FAST-DISINTEGRATING TABLET

ORAL FAST-DISINTEGRATING TABLET

BY COMPRESSION-MOLDING A MIXED POWDER OF A USEFUL BACTERIUM, SILICIFIED MICROCRYSTALLINE CELLULOSE (AN EXCIPIENT THAT IS PRODUCED BY MIXING CRYSTALLINE CELLULOSE AND A SMALL AMOUNT OF LIGHT ANHYDROUS SILICIC ACID IN THE SLURRY FORM AND THEN BY SPRAY-DRYING IT) AND A STARCH-CONTAINING SACCHARIDE (A S...

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Bibliographische Detailangaben
Hauptverfasser: MOTEGI, SACHIO, NOZAKI, MASATSUGU, MATSUMOTO, KANA
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:BY COMPRESSION-MOLDING A MIXED POWDER OF A USEFUL BACTERIUM, SILICIFIED MICROCRYSTALLINE CELLULOSE (AN EXCIPIENT THAT IS PRODUCED BY MIXING CRYSTALLINE CELLULOSE AND A SMALL AMOUNT OF LIGHT ANHYDROUS SILICIC ACID IN THE SLURRY FORM AND THEN BY SPRAY-DRYING IT) AND A STARCH-CONTAINING SACCHARIDE (A STARCH POWDER, A GRANULATED STARCH, A GRANULATED MIXTURE OF STARCH AND LACTOSE) IN THE DRY FORM TO OBTAIN A TABLET WITH A TABLE HARDNESS OF ABOUT 30N-60N, A MOISTURE CONTENT OF 3.2% BY WEIGHT OR LESS, AN ORAL FAST-DISINTEGRATING TABLET OF A USEFUL BACTERIUM SUCH AS A BIFIDOBACTERIUM OR A LACTIC ACID BACTERIUM HAVING A HIGH STABILITY IN TABLET MAKING AND STORAGE STABILITY CAN BE OBTAINED.