A METHOD FOR THE MASS PRODUCTION OF IMMUNOGLOBULIN FC REGION DELETED INITIAL METHIONINE RESIDUES

A METHOD FOR THE MASS PRODUCTION OF IMMUNOGLOBULIN FC REGION DELETED INITIAL METHIONINE RESIDUES

DISCLOSED IS A METHOD FOR THE MASS PRODUCTION OF A MONOMERIC OR DIMERIC IMMUNOGLOBULIN FC REGION, FREE OF INITIAL METHIONINE RESIDUES, USING A RECOMBINANT EXPRESSION VECTOR COMPRISING A NUCLEOTIDE SEQUENCE CODING FOR A RECOMBINANT IMMUNOGLOBULIN FC REGION COMPRISING AN IMMUNOGLOBULIN FC REGION LINKE...

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Bibliographische Detailangaben
Hauptverfasser: LEE, GWAN-SUN, JUNG, SUNG YOUB, CHOI, KI DOO, KIM, JIN SUN, SHIN, JIN HWAN, KWON, SEANG, SONG, DAE HAE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Zusammenfassung:DISCLOSED IS A METHOD FOR THE MASS PRODUCTION OF A MONOMERIC OR DIMERIC IMMUNOGLOBULIN FC REGION, FREE OF INITIAL METHIONINE RESIDUES, USING A RECOMBINANT EXPRESSION VECTOR COMPRISING A NUCLEOTIDE SEQUENCE CODING FOR A RECOMBINANT IMMUNOGLOBULIN FC REGION COMPRISING AN IMMUNOGLOBULIN FC REGION LINKED AT THE N-TERMINUS THEREOF TO AN IMMUNOGLOBULIN FC REGION VIA A PEPTIDE BOND.