COMPOUNDS WHICH HAVE ACTIVITY AT M? RECEPTOR AND THEIR USES IN MEDICINE

COMPOUNDS WHICH HAVE ACTIVITY AT M? RECEPTOR AND THEIR USES IN MEDICINE

COMPOUNDS OF FORMULA (I) AND SALTS AND SOLVATES ARE PROVIDED: WHEREIN R? IS FLUORO, R? IS SELECTED FROM HYDROGEN, HALOGEN, CYANO, C?-?ALKYL, C?-?ALKYL SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, C?-?ALKOXY, AND C?-?ALKOXY SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, AND R? IS SELECTED FROM HALOGEN,...

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Bibliographische Detailangaben
Hauptverfasser: JIN, JIAN, WALKER, GRAHAM, SMITH, PAUL, WILLIAM, GARZYA, VINCENZO, BUDZIK, BRIAN, FORBES, IAN THOMSON, SHI, DONGCHUAN, COOPER, DAVID, GWYN
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:COMPOUNDS OF FORMULA (I) AND SALTS AND SOLVATES ARE PROVIDED: WHEREIN R? IS FLUORO, R? IS SELECTED FROM HYDROGEN, HALOGEN, CYANO, C?-?ALKYL, C?-?ALKYL SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, C?-?ALKOXY, AND C?-?ALKOXY SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, AND R? IS SELECTED FROM HALOGEN, CYANO, C?-?ALKYL, C?-?ALKYL SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, C? -?CYCLOALKYL, C? -?CYCLOALKYL SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, C?-?ALKOXY AND C?-?ALKOXY SUBSTITUTED WITH ONE OR MORE FLUORINE ATOMS, AND Q IS HYDROGEN OR C?-?ALKYL. THE COMPOUNDS ARE EXPECTED TO BE USEFUL FOR THERAPY, FOR EXAMPLE IN THE TREATMENT OF PSYCHOTIC DISORDERS AND COGNITIVE IMPAIRMENT.