A METHOD FOR SYNTHESIZING POLYHYDROXYLATED FLAVANOIDS

A METHOD FOR SYNTHESIZING POLYHYDROXYLATED FLAVONOIDS VIA A CHALCONE, COMPRISING THE STEPS OF PREPARING A HYDROXYACETOPHENONE OR A DERIVATIVE THEREOF AND A BENZALDEHYDE OR A DERIVATIVE THEREOF BY PROTECTING THEIR PHENOLIC HYDROXYL GROUPS; REACTING THE HYDROXYACETOPHENONE OR THE DERIVATIVE THEREOF WI...

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Hauptverfasser: FAREDIAH BINTI AHMAD, MUHAMMAD SUM BIN HJ. IDRIS, ADIANA BINTI MOHAMED ADIB
Format: Patent
Sprache:eng
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Zusammenfassung:A METHOD FOR SYNTHESIZING POLYHYDROXYLATED FLAVONOIDS VIA A CHALCONE, COMPRISING THE STEPS OF PREPARING A HYDROXYACETOPHENONE OR A DERIVATIVE THEREOF AND A BENZALDEHYDE OR A DERIVATIVE THEREOF BY PROTECTING THEIR PHENOLIC HYDROXYL GROUPS; REACTING THE HYDROXYACETOPHENONE OR THE DERIVATIVE THEREOF WITH THE BENZALDEHYDE OR THE DERIVATIVE THEREOF TO PRODUCE THE CHALCONE; REFLUXING THE CHALCONE WITH AN ACID TO REMOVE THE PROTECTED GROUPS; TREATING THE REFLUXED CHALCONE WITH EXCESS SODIUM ACETATE; AND COMPLETING THE REFLUX PROCESS TO OBTAIN A POLYHYDROXYFLAVANONE.