BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION

BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION

THE INVENTION PROVIDES FOR A PHARMACEUTICAL COMPOSITION CAPABLE OF MODULATING THE ANDROGEN RECEPTOR COMPRISING A COMPOUND OF FORMULA I WHEREIN THE SUBSTITUTENTS ARE AS DESCRIBED HEREIN. FURTHER PROVIDED ARE METHODS OF USING SUCH COMPOUNDS FOR THE TREATMENT OF NUCLEAR HORMONE RECEPTOR-ASSOCIATED COND...

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Bibliographische Detailangaben
Hauptverfasser: JEFFREY ROBL, LIGAYA SIMPKINS, CHONGQING SUN, LAWRENCE HAMANN, YAN-TING HUANG, ALEXANDRA HOLUBEC, DAVID AUGERI, YINGZHI BI, TAMMY WANG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:THE INVENTION PROVIDES FOR A PHARMACEUTICAL COMPOSITION CAPABLE OF MODULATING THE ANDROGEN RECEPTOR COMPRISING A COMPOUND OF FORMULA I WHEREIN THE SUBSTITUTENTS ARE AS DESCRIBED HEREIN. FURTHER PROVIDED ARE METHODS OF USING SUCH COMPOUNDS FOR THE TREATMENT OF NUCLEAR HORMONE RECEPTOR-ASSOCIATED CONDITIONS, SUCH AS AGE RELATED DISEASES, FOR EXAMPLE SARCOPENIA. ALSO PROVIDED ARE PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND PROCESSES FOR PREPARING SOME OF THE COMPOUNDS OF THE INVENTION.