HIGHLY SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS AND METHODS OF USING THE SAME

METHODS AND COMPOSITIONS FOR TREATING HUMANS SUFFERING FROM , OR PREVENTING A HUMAN FROM SUFFERING , A PHYSIOLOGICAL OR PSYCHIATRIC DISEASE, DISORDER , OR A CONDITION WHERE INHIBITING REUPTAKE OF NOREPINEPHRINE IS A BENEFIT ARE DISCLOSED . THE COMPOSITIONS COMPRISE A COMPOUND HAVING A PHARMACOLOGICA...

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Hauptverfasser: SAEEDUDDIN AHMED, ROBERT MCARTHUR, DUNCAN P. TAYLOR, ERIK H.F. WONG, ROBERT CLYDE MARSHALL, PASQUALE CETERA, LARS BIRGERSON
Format: Patent
Sprache:eng
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Zusammenfassung:METHODS AND COMPOSITIONS FOR TREATING HUMANS SUFFERING FROM , OR PREVENTING A HUMAN FROM SUFFERING , A PHYSIOLOGICAL OR PSYCHIATRIC DISEASE, DISORDER , OR A CONDITION WHERE INHIBITING REUPTAKE OF NOREPINEPHRINE IS A BENEFIT ARE DISCLOSED . THE COMPOSITIONS COMPRISE A COMPOUND HAVING A PHARMACOLOGICAL SELECTIVITY OF SEROTIN (K1)/NOREPINEPHRINE (K1) OF AT LEAST ABOUT 5000 . EXAMPLES OF SUCH COMPOUNDS INCLUDE REBOXETINE , AND MORE PREFERABLY OPTICALLY (S,S) ENANTIOMER OF REBOXETINE. THE METHODS GENERALLY INCLUDE ADMINISTRATION OF A AMOUNT OF SUCH COMPOSITIONS. ALSO DISCLOSED ARE PREPARATIONS OF A MEDICAMENT FROM THE COMPOSITION, AND USES OF THE COMPOSITION IN A MANUFACTURE OF THE MEDICAMENT TO TREAT A HUMAN SUFFERING FROM, OR PREVENTING A HUMAN FROM SUFFERING , A PHYSIOLOGICAL OR PSYCHIATRIC DISEASE , DISORDER , OR CONDITION .