EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS

THIS INVENTION PROVIDES NOVEL DECAHYDROISOQUINOLINE COMPOUNDS WHICH ARE ARE USEFUL AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS AND IN THE TREATMENT OF NEUROLOGICAL DISORDERS. THIS INVENTION ALSO PROVIDES SYNTHETIC METHODS FOR PREPARING DECAHYDROISOQUILINES, AS WELL AS, NOVEL INTERMEDIATES IN THE S...

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Hauptverfasser: ALLEN ROBERT HARKNESS, MICHAEL JOHN MARTINELLI, CARL FRANKLIN BERTSCH, DARRYLE DARWIN SCHOEPP, NANCY KAY AUGENSTEIN, PAUL LESLIE ORNSTEIN, MARVIN MARTIN HANSEN, BRET EUGENE HUFF, MACKLIN BRIAN ARNOLD, WILLIAM HENRY WALKER LUNN
Format: Patent
Sprache:eng
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Zusammenfassung:THIS INVENTION PROVIDES NOVEL DECAHYDROISOQUINOLINE COMPOUNDS WHICH ARE ARE USEFUL AS EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS AND IN THE TREATMENT OF NEUROLOGICAL DISORDERS. THIS INVENTION ALSO PROVIDES SYNTHETIC METHODS FOR PREPARING DECAHYDROISOQUILINES, AS WELL AS, NOVEL INTERMEDIATES IN THE SYNTHESIS THEREOF.