METHOD FOR THE PRODUCTION OF PROTEINS IN PLANT FLUIDS

A METHOD OF PRODUCING A GENETICALLY TRANSFORMED FLUID-PRODUCING PLANT COMPRISES:-I)INSERTING INTO THE PLANT TISSUE A GENE OR GENE FRAGMENT CONTROLLING THE EXPRESSION OF A TARGET PRODUCT, AND II)REGENERATING A PLANT FROM SAID TISSUE, THE GENETICALLY TRANFORMED PLANT BEING CAPABLE OF EXPRESSING THE TA...

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Hauptverfasser: WAN ABDUL RAHMAN WAN YAACOB, YEANG HOON YEET, PAPPUSAMY AROKIARAJ, STEPHEN A. BOFFEY, CHEONG KAY FONG, HEDDWYN JONES, ROBERT J. SLATER
Format: Patent
Sprache:eng
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Zusammenfassung:A METHOD OF PRODUCING A GENETICALLY TRANSFORMED FLUID-PRODUCING PLANT COMPRISES:-I)INSERTING INTO THE PLANT TISSUE A GENE OR GENE FRAGMENT CONTROLLING THE EXPRESSION OF A TARGET PRODUCT, AND II)REGENERATING A PLANT FROM SAID TISSUE, THE GENETICALLY TRANFORMED PLANT BEING CAPABLE OF EXPRESSING THE TARGET PRODUCT IN THE FLUID THAT IT PRODUCES.THERE ARE ALSO PROVIDED CLONES OF GENETICALLY TRANSFORMED FLUID-PRODUCING PLANTS WHICH CONTAIN IN THEIR CELLS A CHROMOSOMAL INSERT SUCH THAT THE TARGET PRODUCT IS EXPRESSED IN THE FLUIDS THAT THE PLANTS PRODUCE. THERE IS FURTHER DESCRIBED A METHOD OF PRODUCING A PORTEIN OR OTHER TARGET PRODUCT WHICH COMPRISES:-I)HARVESTING THE FLUID FROM A GENETICALLY TRANSFORMED FLUID-PRODUCING TREE OR PLANT, OR A CLONE THEREOF, AND II)RECOVERING THE TARGET PROTEIN OR OTHER PRODUCT FROM SAID FLUID.MOST PREFERABLY, THE PLANTS ARE RUBBER (HEVEA) PLANTS ARE THE GENES THAT CODE FOR PHARMACEUTICALLY VALUABLE PROTEIN PRODUCTS WHICH CAN BE HARVESTED IN THE LATEX PRODUCED BY THE PLANTS.(FIG. 1)