NEW CONTROLLED RELEASE BEAD, A METHOD OF PRODUCING THE SAME AND MULTIPLE UNIT FORMULATION COMPRISING IT

NEW CONTROLLED RELEASE BEAD, A METHOD OF PRODUCING THE SAME AND MULTIPLE UNIT FORMULATION COMPRISING IT

A CONTROLLED RELEASE BEAD COMPRISES: (I) A CORE UNIT OF A SUBSTANTIALLY WATER-SOLUBLE OR WATER-SWELLABLE INERT MATERIAL; (II) A FIRST LAYER ON THE CORE UNIT OF A SUBSTANTIALLY WATER-INSOLUBLE POLYMER; (III) A SECOND LAYER COVERING THE FIRST LAYER AND CONTAINING AN ACTIVE INGREDIENT; AND (IV) A THIRD...

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Bibliographische Detailangaben
Hauptverfasser: ANDERS RINGBERG, TORKEL GREN, MARTIN WIKBERG, RANDY J. WALD
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:A CONTROLLED RELEASE BEAD COMPRISES: (I) A CORE UNIT OF A SUBSTANTIALLY WATER-SOLUBLE OR WATER-SWELLABLE INERT MATERIAL; (II) A FIRST LAYER ON THE CORE UNIT OF A SUBSTANTIALLY WATER-INSOLUBLE POLYMER; (III) A SECOND LAYER COVERING THE FIRST LAYER AND CONTAINING AN ACTIVE INGREDIENT; AND (IV) A THIRD LAYER OF POLYMER ON THE SECOND LAYER EFFECTIVE FOR CONTROLLED RELEASE OF THE ACTIVE INGREDIENT, WHEREIN THE FIRST LAYER IS ADAPTED TO CONTROL WATER PENETRATION INTO THE CORE. A METHOD OF PRODUCING THE CONTROLLED RELASE BEAD IS ALSO DISCLOSED.