PRODRUGS OF THROMBIN INHIBITORS

THERE IS PROVIDED COMPOUNDS OF FORMULA I.R1O(O)C-CH2(R)CGL-AZE-PAB-R2WHEREIN R1 AND R2 HAVE MEANINGS GIVEN IN THE DESCRIPTION, WHICH ARE USEFUL AS PRODRUGS OF INHIBITORS OF TRYPSIN-LIKE PROTEASES, SUCH AS THROMBIN, AND IN PARTICULAR IN THE TREATMENT OF CONDITIONS WHERE INHIBITION OF THROMBIN IS REQU...

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Bibliographische Detailangaben
Hauptverfasser: ANTONSSON, THOMAS, NYSTROM, JAN-ERIK, HOFFMANN, KURT-JURGEN, GUSTAFSSON, DAVID, SELLEN, MIKAEL, SORENSEN, HENRIK
Format: Patent
Sprache:eng
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Zusammenfassung:THERE IS PROVIDED COMPOUNDS OF FORMULA I.R1O(O)C-CH2(R)CGL-AZE-PAB-R2WHEREIN R1 AND R2 HAVE MEANINGS GIVEN IN THE DESCRIPTION, WHICH ARE USEFUL AS PRODRUGS OF INHIBITORS OF TRYPSIN-LIKE PROTEASES, SUCH AS THROMBIN, AND IN PARTICULAR IN THE TREATMENT OF CONDITIONS WHERE INHIBITION OF THROMBIN IS REQUIRED (EG THROMBOSIS) OR AS ANTICOAGULANTS.