VISUALLY-READABLE REAGENT TEST STRIP

A MULTILAYER REAGENT TEST STRIP MEASURES THE CONCETRATION OF ANALYTE IN A LIQUIID SAMPLE THAT IS APPLIED TO IT. THE SAMPLE IS GUIDED TO A NUMBER OF ASSAY AREAS ARRAYED ALONG THE STRIP, WHERE THE ANALYTE CAN REACT WITH A REAGENT TO CAUSE A COLOR CHANGE. EACH ASSAY AREA ALSO INCLUDES AN INHIBITOR FOR...

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Hauptverfasser: DEBORAH P. TUOHY, EDWARD G. RICE, ERNEST KISER, ZBIGNIEW WITKO, JOEL DOUGLAS, REMEDIOS DATO, MICHAEL F. TOMASCO, SCOTT SEGELKE, MARK MAXSON
Format: Patent
Sprache:eng
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Zusammenfassung:A MULTILAYER REAGENT TEST STRIP MEASURES THE CONCETRATION OF ANALYTE IN A LIQUIID SAMPLE THAT IS APPLIED TO IT. THE SAMPLE IS GUIDED TO A NUMBER OF ASSAY AREAS ARRAYED ALONG THE STRIP, WHERE THE ANALYTE CAN REACT WITH A REAGENT TO CAUSE A COLOR CHANGE. EACH ASSAY AREA ALSO INCLUDES AN INHIBITOR FOR THE COLOR-CHANGE REACTION. THE INHIBITOR CONCENTRATION INCREASES IN SUCCESSIVE ASSAY AREAS; THUS, THE NUMBER OF AREAS THAT CHANGE COLOR IS A MEASURE OF THE ANALYTE CONCENTRATION. THE TEST STRIP IS PARTICULARLY ADAPTED FOR MEASURING GLUCOSE IN A WHOLE BLOOD SAMPLE. IN A PREFERRED EMBODIMENT, THE SAMPLE IS GUIDED TO THE ASSAY AREAS ALONG A PATH FORMED BY CRUSHING SELECTED AREAS OF A MEMBRANE, AND THE ASSAY AREAS ARE UNCRUSHED AREAS OF THE MEMBRANE.FIGURE 8